Same way, new location:
Control Panel/Folder Options

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Maxwell Bluemeanie
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"Port Admiral Haynes" <spam.th@t.way> wrote in message
news:460ab767$0$22525$fa0fcedb@news.zen.co.uk...
> In XP I could, under folders and options, set my mouse so a single click
> would open an application instead of needing to double click.
>
> Not found out how to do this in Vista yet!